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Slc20a1tm1.2Lbek
Targeted Allele Detail
Nomenclature
Symbol: Slc20a1tm1.2Lbek
Name: solute carrier family 20, member 1; targeted mutation 1.2, Laurent Beck
MGI ID: MGI:4438614
Synonyms: PiT1delta5
Gene: Slc20a1  Location: Chr2:129198764-129211616 bp, + strand  Genetic Position: Chr2, 62.79 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:157997
Parent Cell Line:  CK35 (ES Cell)
Strain of Origin:  129S2/SvPas
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsAn FRT flanked neo cassette was inserted in intron 5, and exon 5 was flanked 5' and 3' with loxP sites 532 bp upstream and 934 bp downstream. The selection cassette and exon 5 were removed by cre mediated recombination. Absence of transcript was confirmed by Northern blot analysis of E12.5 whole embryos. (J:157997)
Phenotypes
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Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Slc20a1 Mutation:  13 strains or lines available
References
Original:  J:157997 Beck L, et al., The phosphate transporter PiT1 (Slc20a1) revealed as a new essential gene for mouse liver development. PLoS One. 2010;5(2):e9148
All:  2 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
07/12/2016
MGI 6.04
The Jackson Laboratory