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Scpep1tm1Jomm
Targeted Allele Detail
Nomenclature
Symbol: Scpep1tm1Jomm
Name: serine carboxypeptidase 1; targeted mutation 1, Joseph M Miano
MGI ID: MGI:4437862
Gene: Scpep1  Location: Chr11:88814846-88846268 bp, - strand  Genetic Position: Chr11, 54.34 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:158052
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  129S/SvEv
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsA targeting vector was designed to replace exons 1-2 of the serine carboxypeptidase 1 (Scpep1) gene with a beta-galactosidase (lacZ) gene and a loxP-flanked neomycin resistance cassette. (J:158052)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Scpep1 Mutation:  69 strains or lines available
References
Original:  J:158052 Lee TH, et al., Functional characterization of a putative serine carboxypeptidase in vascular smooth muscle cells. Circ Res. 2009 Jul 31;105(3):271-8
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
11/23/2021
MGI 6.17
The Jackson Laboratory