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Tg(Cdh5-tTA)D5Lbjn
Transgene Detail
Nomenclature
Symbol: Tg(Cdh5-tTA)D5Lbjn
Name: transgene insertion D5, Laura E Benjamin
MGI ID: MGI:4437711
Synonyms: VE-cadherin:tTA, VE-Cadherin-tTA, Vecad-tTA, VEtTA
Transgene: Tg(Cdh5-tTA)D5Lbjn  Location: unknown  
Transgene
origin
Strain of Origin:  FVB
Transgene
description
Transgene Type:    Transgenic (Inserted expressed sequence)
Mutation:    Insertion
 
Mutation detailsThe Cdh5 (VE-cadherin) promoter was inserted upstream of the tetracycline-regulated transcriptional activator (tTA) gene. Four founder lines were tested and found to show similar performance. The D5 line was analyzed further. (J:95750)
Phenotypes
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Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
References
Original:  J:95750 Sun JF, et al., Microvascular patterning is controlled by fine-tuning the Akt signal. Proc Natl Acad Sci U S A. 2005 Jan 4;102(1):128-33
All:  30 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
11/23/2021
MGI 6.17
The Jackson Laboratory