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Ush1ctm1Xzl
Targeted Allele Detail
Nomenclature
Symbol: Ush1ctm1Xzl
Name: Usher syndrome 1C; targeted mutation 1, Xue Liu
MGI ID: MGI:4437562
Gene: Ush1c  Location: Chr7:46195350-46238503 bp, - strand  Genetic Position: Chr7, 29.66 cM, cytoband B3
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:158047
Parent Cell Line:  R1 (ES Cell)
Strain of Origin:  (129X1/SvJ x 129S1/Sv)F1-Kitl+
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsThe first four exons were replaced with a Beta galactosidase reporter and neomycin resistance genes, successfully eliminating expression of all of the many transcripts produced by this gene, including a, b, and c isoforms. (J:158047)
Phenotypes
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View phenotypes for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Ush1c Mutation:  8 strains or lines available
References
Original:  J:158047 Tian C, et al., Ush1c gene expression levels in the ear and eye suggest different roles for Ush1c in neurosensory organs in a new Ush1c knockout mouse. Brain Res. 2010 Apr 30;1328:57-70
All:  4 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
03/24/2015
MGI 5.21
The Jackson Laboratory