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Ptprttm1Sata
Targeted Allele Detail
Nomenclature
Symbol: Ptprttm1Sata
Name: protein tyrosine phosphatase, receptor type, T; targeted mutation 1, Masanobu Satake
MGI ID: MGI:4437410
Synonyms: PTPRT-, Ptprttm1Zhw
Gene: Ptprt  Location: Chr2:161363910-162503067 bp, - strand  Genetic Position: Chr2, 81.91 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:157542
Parent Cell Line:  E14.1 (ES Cell)
Strain of Origin:  129P2/OlaHsd
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsExon 22, containing the phosphatase catalytic core motif of the first catalytic domain, was replaced with a PGK-NeobpA cassette. (J:157542)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Ptprt Mutation:  58 strains or lines available
References
Original:  J:157542 Zhao Y, et al., Identification and functional characterization of paxillin as a target of protein tyrosine phosphatase receptor T. Proc Natl Acad Sci U S A. 2010 Feb 9;107(6):2592-7
All:  3 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
09/27/2022
MGI 6.21
The Jackson Laboratory