About   Help   FAQ
Ptprttm1Sata
Targeted Allele Detail
Nomenclature
Symbol: Ptprttm1Sata
Name: protein tyrosine phosphatase, receptor type, T; targeted mutation 1, Masanobu Satake
MGI ID: MGI:4437410
Synonyms: PTPRT-, Ptprttm1Zhw
Gene: Ptprt  Location: Chr2:161521990-162661147 bp, - strand  Genetic Position: Chr2, 81.91 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:157542
Parent Cell Line:  E14.1 (ES Cell)
Strain of Origin:  129P2/OlaHsd
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsExon 22, containing the phosphatase catalytic core motif of the first catalytic domain, was replaced with a PGK-NeobpA cassette. (J:157542)
Phenotypes
Loading...
View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Structures Affected by this Mutation: 1 anatomical structures
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Ptprt Mutation:  55 strains or lines available
References
Original:  J:157542 Zhao Y, et al., Identification and functional characterization of paxillin as a target of protein tyrosine phosphatase receptor T. Proc Natl Acad Sci U S A. 2010 Feb 9;107(6):2592-7
All:  2 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
12/04/2018
MGI 6.13
The Jackson Laboratory