Dlg1^tm2.1Jhm
Targeted Allele Detail

Summary

• Symbol: Dlg1^tm2.1Jhm
• Name: discs large MAGUK scaffold protein 1; targeted mutation 2.1, Jeffrey H Miner
• MGI ID: MGI:4437268
• Synonyms: Dlgh1^f
• Gene: Dlg1 Location: Chr16:31482261-31692174 bp, + strand Genetic Position: Chr16, 22.4 cM
• Alliance: Dlg1^tm2.1Jhm page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:129078
• Parent Cell Line: Other (see notes) (ES Cell)
• Strain of Origin: 129 x C57BL/6

Mutation description

• Allele Type: Targeted (Conditional ready, No functional change)
• Mutation: Insertion
• Mutation details: A loxP site was inserted usptream of exon 4 and a floxed neo cassette was inserted downstream. Cre mediated recombination removed the neo cassette leaving exon 4 floxed. (J:129078)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Dlg1 Mutation: 77 strains or lines available

Notes

ES cell line = F1BS

References

• Original: J:129078 Stephenson LM, et al., DLGH1 is a negative regulator of T-lymphocyte proliferation. Mol Cell Biol. 2007 Nov;27(21):7574-81
• All: 6 reference(s)