About   Help   FAQ
Dhx58tm1Aki
Targeted Allele Detail
Nomenclature
Symbol: Dhx58tm1Aki
Name: DEXH (Asp-Glu-X-His) box polypeptide 58; targeted mutation 1, Shizuo Akira
MGI ID: MGI:4437255
Gene: Dhx58  Location: Chr11:100694884-100704271 bp, - strand  Genetic Position: Chr11, 63.52 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:156867
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  Not Specified
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsExons 1-5 were replaced by a neo cassette. Northern blot analysis failed to detect mRNA in homozygous MEFs. (J:156867)
Phenotypes
Loading...
View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Dhx58 Mutation:  16 strains or lines available
References
Original:  J:156867 Satoh T, et al., LGP2 is a positive regulator of RIG-I- and MDA5-mediated antiviral responses. Proc Natl Acad Sci U S A. 2010 Jan 26;107(4):1512-7
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
03/14/2017
MGI 6.08
The Jackson Laboratory