Psap^{tm1e(EUCOMM)Hmgu}
Targeted Allele Detail

Summary

• Symbol: Psap^{tm1e(EUCOMM)Hmgu}
• Name: prosaposin; targeted mutation 1e, Helmholtz Zentrum Muenchen GmbH
• MGI ID: MGI:4435842
• Gene: Psap Location: Chr10:60113449-60138376 bp, + strand Genetic Position: Chr10, 30.02 cM
• IMPC: Psap gene page

Mutation origin

• Mutant Cell Lines: HEPD0537_3_A07, HEPD0537_3_C09, HEPD0537_3_D07, HEPD0537_3_D08, HEPD0537_3_D09, HEPD0537_3_E07, HEPD0537_3_E08, HEPD0537_3_F07, HEPD0537_3_F08, HEPD0537_3_F09, HEPD0537_3_G07, HEPD0537_3_G08, HEPD0537_3_G09, HEPD0537_3_H07, HEPD0537_3_H08
• Germline Transmission: Unknown
• Parent Cell Line: JM8.N4 (ES Cell)
• Strain of Origin: C57BL/6N
• Project Collection: EUCOMM

Mutation description

• Allele Type: Targeted (Null/knockout, Reporter)
• Mutation: Insertion Vector: L1L2_st1
• Mutation details: The L1L2_st1 cassette was inserted at position 60126966 of Chromosome 10 upstream of the critical exon(s) (Build GRCm39). The cassette is composed of an FRT flanked lacZ/neomycin sequence followed by a loxP site. Insertion of this cassette creates a reporter knockout mouse. Cre expression will remove the neomycin selection cassette. Further information on targeting strategies used for this and other IKMC alleles can be found at http://www.informatics.jax.org/mgihome/nomen/IKMC_schematics.shtml (J:157065)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Psap Mutation: 33 strains or lines available

References

• Original: J:157065 Helmholtz Zentrum Muenchen GmbH, Alleles produced for the EUCOMM and EUCOMMTools projects by the Helmholtz Zentrum Muenchen GmbH (Hmgu). MGI Direct Data Submission. 2010-2015
• All: 1 reference(s)