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Snf8tm1a(EUCOMM)Hmgu
Targeted Allele Detail
Nomenclature
Symbol: Snf8tm1a(EUCOMM)Hmgu
Name: SNF8, ESCRT-II complex subunit, homolog (S. cerevisiae); targeted mutation 1a, Helmholtz Zentrum Muenchen GmbH
MGI ID: MGI:4435154
Gene: Snf8  Location: Chr11:96034885-96047430 bp, + strand  Genetic Position: Chr11, 59.24 cM
Mutation
origin
Mutant Cell Lines:  HEPD0502_4_A05, HEPD0502_4_A06, HEPD0502_4_B05, HEPD0502_4_B06, HEPD0502_4_C04, HEPD0502_4_C06, HEPD0502_4_D05, HEPD0502_4_E04, HEPD0502_4_E05, HEPD0502_4_E06, HEPD0502_4_F04, HEPD0502_4_F05, HEPD0502_4_G04, HEPD0502_4_G05, HEPD0502_4_G06, HEPD0502_4_H04, HEPD0502_4_H05 (Helmholtz Zentrum Muenchen GmbH)
Germline Transmission:  Unknown
Parent Cell Line:  JM8.N4 (ES Cell)
Strain of Origin:  C57BL/6N
Project Collection: EUCOMM
Mutation
description
Allele Type:    Targeted (Conditional ready, Null/knockout, Reporter)
Mutation:    Insertion     Vector: L1L2_gt0
 
Mutation detailsThe L1L2_gt0 cassette was inserted at position 96038995 of Chromosome 11 upstream of the critical exon(s) (Build GRCm38). The cassette is composed of an FRT flanked lacZ/neomycin sequence followed by a loxP site. An additional loxP site is inserted downstream of the targeted exon(s) at position 96039653. The critical exon(s) is/are thus flanked by loxP sites. A "conditional ready" (floxed) allele can be created by flp recombinase expression in mice carrying this allele. Subsequent cre expression results in a knockout mouse. If cre expression occurs without flp expression, a reporter knockout mouse will be created. Further information on targeting strategies used for this and other KOMP alleles can be found at http://www.knockoutmouse.org/aboutkompstrategies. (J:157065)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Snf8 Mutation:  6 strains or lines available
References
Original:  J:157065 Helmholtz Zentrum Muenchen GmbH, Alleles produced for the EUCOMM and EUCOMMTools projects by the Helmholtz Zentrum Muenchen GmbH (Hmgu). MGI Direct Data Submission. 2010-2015;
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
03/21/2017
MGI 6.08
The Jackson Laboratory