Plekhm1^{tm1e(EUCOMM)Hmgu}
Targeted Allele Detail

Summary

• Symbol: Plekhm1^{tm1e(EUCOMM)Hmgu}
• Name: pleckstrin homology domain containing, family M (with RUN domain) member 1; targeted mutation 1e, Helmholtz Zentrum Muenchen GmbH
• MGI ID: MGI:4434768
• Gene: Plekhm1 Location: Chr11:103255101-103303513 bp, - strand Genetic Position: Chr11, 67.09 cM
• IMPC: Plekhm1 gene page

Mutation origin

• Mutant Cell Lines: HEPD0506_2_A04, HEPD0506_2_A06, HEPD0506_2_B04, HEPD0506_2_B05, HEPD0506_2_D06, HEPD0506_2_E05, HEPD0506_2_E06, HEPD0506_2_F06, HEPD0506_2_G04, HEPD0506_2_G05, HEPD0506_2_H06
• Germline Transmission: Unknown
• Parent Cell Line: JM8.N4 (ES Cell)
• Strain of Origin: C57BL/6N
• Project Collection: EUCOMM

Mutation description

• Allele Type: Targeted (Null/knockout, Reporter)
• Mutation: Insertion Vector: L1L2_gt0
• Mutation details: The L1L2_gt0 cassette was inserted at position 103288556 of Chromosome 11 upstream of the critical exon(s) (Build GRCm39). The cassette is composed of an FRT flanked lacZ/neomycin sequence followed by a loxP site. Insertion of this cassette creates a reporter knockout mouse. Cre expression will remove the neomycin selection cassette. Further information on targeting strategies used for this and other IKMC alleles can be found at http://www.informatics.jax.org/mgihome/nomen/IKMC_schematics.shtml (J:157065)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Plekhm1 Mutation: 203 strains or lines available

References

• Original: J:157065 Helmholtz Zentrum Muenchen GmbH, Alleles produced for the EUCOMM and EUCOMMTools projects by the Helmholtz Zentrum Muenchen GmbH (Hmgu). MGI Direct Data Submission. 2010-2015
• All: 1 reference(s)