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Ctnnal1tm1e(EUCOMM)Wtsi
Targeted Allele Detail
Nomenclature
Symbol: Ctnnal1tm1e(EUCOMM)Wtsi
Name: catenin (cadherin associated protein), alpha-like 1; targeted mutation 1e, Wellcome Trust Sanger Institute
MGI ID: MGI:4434204
Gene: Ctnnal1  Location: Chr4:56810935-56865188 bp, - strand  Genetic Position: Chr4, 31.66 cM, cytoband C1
Mutation
origin
Mutant Cell Lines:  EPD0019_1_B01, EPD0019_1_C03, EPD0019_1_D03, EPD0019_1_F02 (Wellcome Trust Sanger Institute)
Germline Transmission:  Earliest citation of germline transmission: J:204812
Parent Cell Line:  JM8 (ES Cell)
Strain of Origin:  C57BL/6N
Project Collection: EUCOMM
Mutation
description
Allele Type:    Targeted (Null/knockout, Reporter)
Mutation:    Insertion     Vector: L1L2_st0
 
Mutation detailsThe L1L2_st0 cassette was inserted at position 56848485 of Chromosome 4 upstream of the critical exon(s) (Build GRCm38). The cassette is composed of an FRT flanked lacZ/neomycin sequence followed by a loxP site. Insertion of this cassette creates a reporter knockout mouse. Cre expression will remove the neomycin selection cassette. Further information on targeting strategies used for this and other KOMP alleles can be found at http://www.knockoutmouse.org/aboutkompstrategies. (J:155845, J:173534)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Ctnnal1 Mutation:  154 strains or lines available
References
Original:  J:155845 Wellcome Trust Sanger Institute, Alleles produced for the EUCOMM and EUCOMMTools projects by the Wellcome Trust Sanger Institute. MGI Direct Data Submission. 2010;
All:  4 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
03/21/2017
MGI 6.08
The Jackson Laboratory