Fuca1^{tm1e(EUCOMM)Wtsi}
Targeted Allele Detail

Summary

• Symbol: Fuca1^{tm1e(EUCOMM)Wtsi}
• Name: fucosidase, alpha-L- 1, tissue; targeted mutation 1e, Wellcome Trust Sanger Institute
• MGI ID: MGI:4432048
• Gene: Fuca1 Location: Chr4:135648037-135667611 bp, + strand Genetic Position: Chr4, 68.01 cM, cytoband D3
• IMPC: Fuca1 gene page

Mutation origin

• Mutant Cell Lines: EPD0381_3_A02, EPD0381_3_A03, EPD0381_3_A04, EPD0381_3_A06, EPD0381_3_A07, EPD0381_3_A08, EPD0381_3_A09, EPD0381_3_A10, EPD0381_3_A11, EPD0381_3_A12, EPD0381_3_B01, EPD0381_3_B02, EPD0381_3_B03, EPD0381_3_B04, EPD0381_3_B05, EPD0381_3_B06, EPD0381_3_B07, EPD0381_3_B08, EPD0381_3_B09, EPD0381_3_B10, EPD0381_3_B11, EPD0381_3_C01, EPD0381_3_C02, EPD0381_3_C04, EPD0381_3_C06, EPD0381_3_C07, EPD0381_3_C08, EPD0381_3_C09, EPD0381_3_C10, EPD0381_3_C11, EPD0381_3_C12, EPD0381_3_D01, EPD0381_3_D02, EPD0381_3_D03, EPD0381_3_D04, EPD0381_3_D05, EPD0381_3_D08, EPD0381_3_D09, EPD0381_3_D10, EPD0381_3_D12, EPD0381_3_E03, EPD0381_3_E04, EPD0381_3_E05, EPD0381_3_E06, EPD0381_3_E07, EPD0381_3_E08, EPD0381_3_E09, EPD0381_3_E10, EPD0381_3_E11, EPD0381_3_E12, EPD0381_3_F03, EPD0381_3_F04, EPD0381_3_F05, EPD0381_3_F06, EPD0381_3_F09, EPD0381_3_F10, EPD0381_3_F11, EPD0381_3_F12, EPD0381_3_G02, EPD0381_3_G03, EPD0381_3_G04, EPD0381_3_G05, EPD0381_3_G06, EPD0381_3_G07, EPD0381_3_G08, EPD0381_3_G09, EPD0381_3_G10, EPD0381_3_G12, EPD0381_3_H01, EPD0381_3_H02, EPD0381_3_H04, EPD0381_3_H05, EPD0381_3_H06, EPD0381_3_H07, EPD0381_3_H08, EPD0381_3_H09, EPD0381_3_H10, EPD0381_3_H11
• Germline Transmission: Unknown
• Parent Cell Line: JM8A3.N1 (ES Cell)
• Strain of Origin: C57BL/6N-A^tm1Brd
• Project Collection: EUCOMM

Mutation description

• Allele Type: Targeted (Null/knockout, Reporter)
• Mutation: Insertion Vector: L1L2_Bact_P
• Mutation details: The L1L2_Bact_P cassette was inserted at position 135656715 of Chromosome 4 upstream of the critical exon(s) (Build GRCm39). The cassette is composed of an FRT site followed by lacZ sequence and a loxP site. This first loxP site is followed by a neomycin resistance gene under the control of the human beta-actin promoter, SV40 polyA, a second FRT site and a second loxP site. Insertion of this cassette creates a reporter knockout mouse. Cre expression will remove the neomycin selection cassette. Further information on targeting strategies used for this and other IKMC alleles can be found at http://www.informatics.jax.org/mgihome/nomen/IKMC_schematics.shtml (J:155845, J:173534)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Fuca1 Mutation: 31 strains or lines available

References

• Original: J:155845 Wellcome Trust Sanger Institute, Alleles produced for the EUCOMM and EUCOMMTools projects by the Wellcome Trust Sanger Institute. MGI Direct Data Submission. 2010
• All: 2 reference(s)