Del(14)1.1Hsak
Targeted Allele Detail

Summary

• Symbol: Del(14)1.1Hsak
• Name: deletion, Chr 14, Hitoshi Sakano 1.1
• MGI ID: MGI:4431387
• Synonyms: Del1.1Hsak, H^-
• Gene: Del(14)1.1Hsak Location: unknown Genetic Position: Chr14, Syntenic

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:128605
• Parent Cell Line: D3 (ES Cell)
• Strain of Origin: 129S2/SvPas

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutation: Intergenic deletion
• Del(14)1.1Hsak involves 3 genes/genome features (Or4e2, Or4e1, Or4e5) View all
• Mutation details: The 187 bp of the core-H sequence upstream of Olfr1507 was replaced with an frt-flanked neo cassette. Flp mediated recombination removed the neo cassette. Loss of transcript expression of Olfr1507, Olfr1508, and Olfr1509 was confirmed by in situ hybridization. (J:128605)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Del(14)1.1Hsak Mutation: 0 strains or lines available

References

• Original: J:128605 Nishizumi H, et al., Deletion of the core-H region in mice abolishes the expression of three proximal odorant receptor genes in cis. Proc Natl Acad Sci U S A. 2007 Dec 11;104(50):20067-72
• All: 1 reference(s)