Kcnn1^tm1.2Jpad
Targeted Allele Detail

Summary

• Symbol: Kcnn1^tm1.2Jpad
• Name: potassium intermediate/small conductance calcium-activated channel, subfamily N, member 1; targeted mutation 1.2, John P Adelman
• MGI ID: MGI:4431001
• Gene: Kcnn1 Location: Chr8:71294693-71315902 bp, - strand Genetic Position: Chr8, 34.27 cM
• Alliance: Kcnn1^tm1.2Jpad page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:157520
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Conditional ready, No functional change)
• Mutation: Insertion
• Mutation details: A loxP site was inserted 40 nucleotides 5' of the initiation methionine codon in exon 3 and a floxed neomycin resistance gene as well as an EGFP gene were inserted in the intron between exons 5 and 6. The EGFP insert was non functional. Cre mediated recombination removed the neo cassette leaving the loxP sites in exon 3 and intron 5 intact. (J:94941)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Kcnn1 Mutation: 22 strains or lines available

References

• Original: J:157520 Adelman JP, Direct submission. MGI Direct Data Submission. 2010
• All: 2 reference(s)