Tg(Col1a1-tTA)1Niss
Transgene Detail

Summary

• Symbol: Tg(Col1a1-tTA)1Niss
• Name: transgene insertion 1, Robert Nissenson
• MGI ID: MGI:4430728
• Synonyms: Col-I 3.6
• Transgene: Tg(Col1a1-tTA)1Niss Location: unknown
• Alliance: Tg(Col1a1-tTA)1Niss page

Transgene origin

• Strain of Origin: FVB/N

Transgene description

• Transgene Type: Transgenic (Transactivator)
• Mutation: Insertion
• Mutation details: The tetracycline transactivator (tTA) coding sequence is driven by the 3.6-kb promoter from the rat collagen, type 1, alpha 1 gene, which drives expression in both mature and immature osteoblasts. The coding sequence is followed by the rabbit beta-globin intron and a polyadenylation signal. In the absence of tetracycline, expression of a second transgene whose promoter is regulated by the tet operator sequence (tetO) is induced; this induction is suppressed by tetracycline administration. (J:94077)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available

References

• Original: J:94077 Mutant Mouse Regional Resource Centers, Information obtained from the Mutant Mouse Regional Resource Centers (MMRRC). Unpublished. 2004-2015
• All: 1 reference(s)