Ptprc^tm2.1Medv
Targeted Allele Detail

Summary

• Symbol: Ptprc^tm2.1Medv
• Name: protein tyrosine phosphatase receptor type C; targeted mutation 2.1, Alexander Medvinsky
• MGI ID: MGI:4430240
• Synonyms: CD45-YFP
• Gene: Ptprc Location: Chr1:137990599-138103446 bp, - strand Genetic Position: Chr1, 60.73 cM
• Alliance: Ptprc^tm2.1Medv page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:152523
• Parent Cell Line: E14 (ES Cell)
• Strain of Origin: 129P2/OlaHsd

Mutation description

• Allele Type: Targeted (Null/knockout, Reporter)
• Mutation: Insertion
• Mutation details: The YFP encoding cDNA sequence, followed by the SV40 polyadenylation signal and a FRT-flanked puromycin resistance cassette, was inserted at the ATG translation initiation site in the second exon. The selection cassette was deleted by FLPe expression. (J:152523)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Ptprc Mutation: 212 strains or lines available

References

• Original: J:152523 Yang J, et al., Transgenic tools for analysis of the haematopoietic system: knock-in CD45 reporter and deletor mice. J Immunol Methods. 2008 Sep 15;337(2):81-7
• All: 1 reference(s)