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Tg(tetO-Ppargc1a)1Dpk
Transgene Detail
Summary
Symbol: Tg(tetO-Ppargc1a)1Dpk
Name: transgene insertion 1, Daniel P Kelly
MGI ID: MGI:4429485
Synonyms: TRE-PGC-1 alpha
Transgene: Tg(tetO-Ppargc1a)1Dpk  Location: unknown  
Alliance: Tg(tetO-Ppargc1a)1Dpk page
Transgene
origin
Strain of Origin:  FVB
Transgene
description
Transgene Type:    Transgenic (Inducible, Inserted expressed sequence)
Inducer:    doxycycline/tetracycline
Mutation:    Insertion
 
Tg(tetO-Ppargc1a)1Dpk expresses 1 gene
 
Mutation detailsMouse Ppargc1a (peroxisome proliferative activated receptor, gamma, coactivator 1 alpha) cDNA with a C-terminal myc-his tag was placed under the control of the tetracycline operator (tetO). (J:96614)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Disease models
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Expression
In Structures Affected by this Mutation: 3 anatomical structures
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
References
Original:  J:96614 Russell LK, et al., Cardiac-specific induction of the transcriptional coactivator peroxisome proliferator-activated receptor gamma coactivator-1alpha promotes mitochondrial biogenesis and reversible cardiomyopathy in a developmental stage-dependent manner. Circ Res. 2004 Mar 5;94(4):525-33
All:  10 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
11/15/2022
MGI 6.22
The Jackson Laboratory