About   Help   FAQ
Agr2tm1.2Lpkn
Targeted Allele Detail
Nomenclature
Symbol: Agr2tm1.2Lpkn
Name: anterior gradient 2; targeted mutation 1.2, Steven M Lipkin
MGI ID: MGI:4421689
Gene: Agr2  Location: Chr12:35992907-36004087 bp, + strand  Genetic Position: Chr12, 16.18 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:156704
Parent Cell Line:  TL1/TL-1 (ES Cell)
Strain of Origin:  129S6/SvEvTac
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsCre mediated recombination removed exons 2 through 4. The absence of protein expression was confirmed by western blot analysis and immunohistochemistry. (J:156704)
Phenotypes
Loading...
View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Agr2 Mutation:  8 strains or lines available
References
Original:  J:156704 Zhao F, et al., Disruption of Paneth and goblet cell homeostasis and increased endoplasmic reticulum stress in Agr2-/- mice. Dev Biol. 2010 Feb 15;338(2):270-9
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
06/20/2017
MGI 6.10
The Jackson Laboratory