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Agr2tm1.2Lpkn
Targeted Allele Detail
Nomenclature
Symbol: Agr2tm1.2Lpkn
Name: anterior gradient 2; targeted mutation 1.2, Steven M Lipkin
MGI ID: MGI:4421689
Gene: Agr2  Location: Chr12:35992907-36004087 bp, + strand  Genetic Position: Chr12, 16.18 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:156704
Parent Cell Line:  TL1/TL-1 (ES Cell)
Strain of Origin:  129S6/SvEvTac
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsCre mediated recombination removed exons 2 through 4. The absence of protein expression was confirmed by western blot analysis and immunohistochemistry. (J:156704)
Phenotypes
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Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Agr2 Mutation:  7 strains or lines available
References
Original:  J:156704 Zhao F, et al., Disruption of Paneth and goblet cell homeostasis and increased endoplasmic reticulum stress in Agr2-/- mice. Dev Biol. 2010 Feb 15;338(2):270-9
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
11/22/2016
MGI 6.06
The Jackson Laboratory