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Targeted Allele Detail
Symbol: Csf1rtm1Anjm
Name: colony stimulating factor 1 receptor; targeted mutation 1, Andrew N J McKenzie
MGI ID: MGI:4421685
Gene: Csf1r  Location: Chr18:61105572-61131134 bp, + strand  Genetic Position: Chr18, 34.41 cM, cytoband D
Germline Transmission:  Earliest citation of germline transmission: J:155870
Parent Cell Line:  E14.1 (ES Cell)
Strain of Origin:  129P2/OlaHsd
Allele Type:    Targeted (Null/knockout)
Mutation:    Insertion
Mutation detailsThe MICER clone MHPP344i11 containing exon 3-9, loxP and a puro cassette was used to target the gene in ES cells that carried Ars1 tm1Anjm. Clones where the two mutations are in cis were selected to generate mice. (J:155870)
View phenotypes and curated references for all genotypes (concatenated display).
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Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Csf1r Mutation:  28 strains or lines available
Original:  J:155870 Barlow JL, et al., A p53-dependent mechanism underlies macrocytic anemia in a mouse model of human 5q- syndrome. Nat Med. 2010 Jan;16(1):59-66
All:  1 reference(s)

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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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MGI 6.12
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