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Arsitm1Anjm
Targeted Allele Detail
Nomenclature
Symbol: Arsitm1Anjm
Name: arylsulfatase i; targeted mutation 1, Andrew N J McKenzie
MGI ID: MGI:4421684
Gene: Arsi  Location: Chr18:60911780-60918561 bp, + strand  Genetic Position: Chr18, 34.41 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:155870
Parent Cell Line:  E14.1 (ES Cell)
Strain of Origin:  129P2/OlaHsd
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsA loxP flanked neomycin cassette was inserted into exon 2, replacing about a 750 bp fragment of the gene, by homologous recombination. (J:155870)
Phenotypes
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Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Arsi Mutation:  50 strains or lines available
References
Original:  J:155870 Barlow JL, et al., A p53-dependent mechanism underlies macrocytic anemia in a mouse model of human 5q- syndrome. Nat Med. 2010 Jan;16(1):59-66
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
07/19/2016
MGI 6.04
The Jackson Laboratory