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Tg(Ebf2-EGFP/icre)1Ggc
Transgene Detail
Nomenclature
Symbol: Tg(Ebf2-EGFP/icre)1Ggc
Name: transgene insertion 1, Giacomo Consalez
MGI ID: MGI:4421668
Synonyms: Ebf2-Cre
Transgene: Tg(Ebf2-EGFP/icre)1Ggc  Location: unknown  
Transgene
origin
Strain of Origin:  FVB/N
Transgene
description
Transgene Type:    Transgenic (Recombinase)
Mutation:    Insertion
 
Mutation detailsThe BAC clone RP24-283N8 containing 32 kb of 5'flanking sequence plus the first 6 exons of the murine Ebf2 gene was modified to insert the cDNA encoding a fusion of EGFP and the improved cre recombinase (icre) followed by the SV40 polyA signal into the first coding exon of Ebf2. This modified BAC was microinjected into the pronuclei of FVB/N oocytes. Founders were isolated and a line was established. The icre transcript distribution recapitulates that of endogenous Ebf2 transcripts at all locations and stages assayed. (J:156632)
Recombinase
activity
Activity:
 Tissue activity of this recombinase allele
Driver: Ebf2     Summary of all recombinase alleles driven by Ebf2. Comparative matrix view of recombinase activities
 

Phenotypes
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Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
References
Original:  J:156632 Chung SH, et al., Purkinje cell phenotype restricts the distribution of unipolar brush cells. Neuroscience. 2009 Dec 29;164(4):1496-508
All:  3 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
10/08/2019
MGI 6.14
The Jackson Laboratory