Abcg1^tm1Yah
Targeted Allele Detail

Summary

• Symbol: Abcg1^tm1Yah
• Name: ATP binding cassette subfamily G member 1; targeted mutation 1, Yann Herault
• MGI ID: MGI:4421206
• Gene: Abcg1 Location: Chr17:31276668-31336958 bp, + strand Genetic Position: Chr17, 15.8 cM, cytoband A2-B
• Alliance: Abcg1^tm1Yah page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:154298
• Parent Cell Line: HM-1 (ES Cell)
• Strain of Origin: 129P2/OlaHsd-Hprt1^b-m3

Mutation description

• Allele Type: Targeted
• Mutations: Duplication, Insertion
• Abcg1^tm1Yah involves 1 genes/genome features (Abcg1) View all
• Mutation details: This allele contains a duplication of exons 14 and 15 followed by insertion of a neo cassette, loxP site, and 5' Hprt minigene. It was produced in cis with an insertion of a 3' Hprt mini gene, loxP site, and puro cassette between Cbs and Uaf1 (Is(17B1)1Yah) 0.59 Mb away. (J:154298)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Abcg1 Mutation: 45 strains or lines available

References

• Original: J:154298 Pereira PL, et al., A new mouse model for the trisomy of the Abcg1-U2af1 region reveals the complexity of the combinatorial genetic code of down syndrome. Hum Mol Genet. 2009 Dec 15;18(24):4756-4769
• All: 1 reference(s)