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Tg(tetO-SNCA)1Cai
Transgene Detail
Nomenclature
Symbol: Tg(tetO-SNCA)1Cai
Name: transgene insertion 1, Huaibin Cai
MGI ID: MGI:4420977
Synonyms: alpha-syn WT
Transgene: Tg(tetO-SNCA)1Cai  Location: unknown  
Transgene
origin
Strain of Origin:  C57BL/6
Transgene
description
Transgene Type:    Transgenic (Humanized sequence, Inducible, Inserted expressed sequence)
Mutation:    Insertion
 
Tg(tetO-SNCA)1Cai expresses 1 gene
 
Mutation detailsA transgenic vector was generated encoding the human SNCA gene under control of a tetO promoter. The construct was microinjected into fertilized oocytes, and a line of mice was established. (J:156512)
Phenotypes
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Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
References
Original:  J:156512 Lin X, et al., Leucine-rich repeat kinase 2 regulates the progression of neuropathology induced by Parkinson's-disease-related mutant alpha-synuclein. Neuron. 2009 Dec 24;64(6):807-27
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
08/25/2015
MGI 6.0
The Jackson Laboratory