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Slc45a2uw-5Btlr
Chemically induced Allele Detail
Nomenclature
Symbol: Slc45a2uw-5Btlr
Name: solute carrier family 45, member 2; underwhite 5 Bruce Beutler
MGI ID: MGI:4420315
Synonyms: june gloom, Slc45a2m5Btlr
Gene: Slc45a2  Location: Chr15:11000721-11029233 bp, + strand  Genetic Position: Chr15, 5.4 cM
Mutation
origin
Strain of Origin:  C57BL/6J
Project Collection: Beutler Mutagenetix
Mutation
description
Allele Type:    Chemically induced (ENU)
Mutation:    Single point mutation
 
Mutation detailsThis mutation, discovered among G3 progeny of an ENU treated mouse, comprises a T to C transition at nucleotide position 22723 (Genbank genomic region NC_000081 for linear genomic sequence of Slc45a2), in the fifth of the gene's seven exons. This corresponds to nucleotide 1228 of the transcript and is predicted to result in replacement of serine by proline at amino acid position 378, in the eighth transmembrane domain of the protein (S378P). (J:86521, J:156313)
Inheritance:    Recessive
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Structures Affected by this Mutation: 1 anatomical structures
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Slc45a2 Mutation:  42 strains or lines available
References
Original:  J:156313 Du X, et al., June gloom is an allele of Slc45a2 and displays pigmentation defects. MGI Direct Data Submission. 2010;
All:  4 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
05/19/2020
MGI 6.15
The Jackson Laboratory