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Tg(Csf1r-EGFP)1Hume
Transgene Detail
Nomenclature
Symbol: Tg(Csf1r-EGFP)1Hume
Name: transgene insertion 1, David A Hume
MGI ID: MGI:4420302
Synonyms: 7.2fms-EGFP, c-fms-EGFP, Csf1r-EGFP, MacGreen, Tg(Csf1r-Gfp)Hume
Transgene: Tg(Csf1r-EGFP)1Hume  Location: unknown  
Transgene
origin
Strain of Origin:  (C57BL/6 x CBA)F1
Transgene
description
Transgene Type:    Transgenic (Reporter)
Mutation:    Insertion
 
Mutation detailsThe construct had 3.5 kb of sequence flanking exon 2 and the entire intron 2 sequence of the Csf1r gene driving expression of EGFP. This construct was injected into pronuclei of (C57BL/6 x CBA)F1 fertilized eggs. 5 lines that transmitted the transgene were generated, and EGFP expression was readily detected in peritoneal, bone marrow-derived, and broncho-alveolar lavage macrophages from all lines. (J:156311)
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Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
References
Original:  J:156311 Sasmono RT, et al., A macrophage colony-stimulating factor receptor-green fluorescent protein transgene is expressed throughout the mononuclear phagocyte system of the mouse. Blood. 2003 Feb 1;101(3):1155-63
All:  65 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
11/23/2021
MGI 6.17
The Jackson Laboratory