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Suv39h2tm1(KOMP)Wtsi
Targeted Allele Detail
Nomenclature
Symbol: Suv39h2tm1(KOMP)Wtsi
Name: suppressor of variegation 3-9 2; targeted mutation 1, Wellcome Trust Sanger Institute
MGI ID: MGI:4420002
Gene: Suv39h2  Location: Chr2:3455815-3474986 bp, - strand  Genetic Position: Chr2, 1.95 cM, cytoband A
Mutation
origin
Mutant Cell Lines:  EPD0408_2_B05, EPD0408_2_B07, EPD0408_2_C07, EPD0408_2_F07, EPD0408_2_G05, EPD0408_2_H08
Germline Transmission:  Unknown
Parent Cell Line:  JM8A3.N1 (ES Cell)
Strain of Origin:  C57BL/6N-Atm1Brd
Project Collection: KOMP-CSD
Mutation
description
Allele Type:    Targeted (Null/knockout, Reporter)
Mutations:    Insertion, Intragenic deletion     Vector: L1L2_Bact_P
 
Mutation detailsThe insertion of the L1L2_Bact_P cassette created a deletion of size 8407 starting at position 3472662 and ending at position 3464255 of Chromosome 2 (Genome Build GRCm38). This deletion results in the removal of functionally critical exon(s). The cassette is composed of an FRT site followed by lacZ sequence and a loxP site. This first loxP site is followed by a neomycin resistance gene under the control of the human beta-actin promoter, SV40 polyA, a second FRT site and a second loxP site. (J:148605, J:173534)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 1 line available
Carrying any Suv39h2 Mutation:  3 strains or lines available
References
Original:  J:148605 Wellcome Trust Sanger Institute, Alleles produced for the KOMP project by the Wellcome Trust Sanger Institute. MGI Direct Data Submission. 2009;
All:  2 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
02/04/2020
MGI 6.14
The Jackson Laboratory