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Mta3tm3a(KOMP)Wtsi
Targeted Allele Detail
Nomenclature
Symbol: Mta3tm3a(KOMP)Wtsi
Name: metastasis associated 3; targeted mutation 3a, Wellcome Trust Sanger Institute
MGI ID: MGI:4419906
Gene: Mta3  Location: Chr17:83706163-83821516 bp, + strand  Genetic Position: Chr17, 54.53 cM, cytoband E4
Mutation
origin
Mutant Cell Lines:  EPD0011_3_A08, EPD0011_3_B08, EPD0011_3_C08, EPD0011_3_D08, EPD0011_3_F08, EPD0011_3_G08, EPD0011_3_H08 (Wellcome Trust Sanger Institute)
Germline Transmission:  Earliest citation of germline transmission: J:175295
Parent Cell Line:  SI6.C21 (ES Cell)
Strain of Origin:  C57BL/6JCrl
Project Collection: KOMP-CSD
Mutation
description
Allele Type:    Targeted (Conditional ready, Null/knockout, Reporter)
Mutation:    Insertion     Vector: L1L2_gt1
 
Mutation detailsThe L1L2_gt1 cassette was inserted at position 83737837 of Chromosome 17 upstream of the critical exon(s) (Build GRCm38). The cassette is composed of an FRT flanked lacZ/neomycin sequence followed by a loxP site. An additional loxP site is inserted downstream of the targeted exon(s) at position 83738754. The critical exon(s) is/are thus flanked by loxP sites. A "conditional ready" (floxed) allele can be created by flp recombinase expression in mice carrying this allele. Subsequent cre expression results in a knockout mouse. If cre expression occurs without flp expression, a reporter knockout mouse will be created. Further information on targeting strategies used for this and other KOMP alleles can be found at http://www.knockoutmouse.org/aboutkompstrategies. (J:148605, J:173534)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Mta3 Mutation:  129 strains or lines available
References
Original:  J:148605 Wellcome Trust Sanger Institute, Alleles produced for the KOMP project by the Wellcome Trust Sanger Institute. MGI Direct Data Submission. 2009;
All:  4 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
03/21/2017
MGI 6.08
The Jackson Laboratory