Ripk3tm1(KOMP)Wtsi
Targeted Allele Detail
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Symbol: |
Ripk3tm1(KOMP)Wtsi |
Name: |
receptor-interacting serine-threonine kinase 3; targeted mutation 1, Wellcome Trust Sanger Institute |
MGI ID: |
MGI:4419652 |
Gene: |
Ripk3 Location: Chr14:56022452-56026314 bp, - strand Genetic Position: Chr14, 28.19 cM, cytoband C1
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Alliance: |
Ripk3tm1(KOMP)Wtsi page
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IMPC: |
Ripk3 gene page |
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Mutant Cell Lines: |
EPD0374_3_A05, EPD0374_3_A06, EPD0374_3_B06, EPD0374_3_B07, EPD0374_3_C05, EPD0374_3_C06, EPD0374_3_C08, EPD0374_3_D06, EPD0374_3_E07, EPD0374_3_F08, EPD0374_3_G06, EPD0374_3_G07, EPD0374_3_G08, EPD0374_3_H07 |
Germline Transmission: |
Earliest citation of germline transmission:
J:204812
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Parent Cell Line: |
JM8A3.N1 (ES Cell)
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Strain of Origin: |
C57BL/6N-Atm1Brd
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Project Collection: |
KOMP-CSD
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Allele Type: |
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Targeted (Null/knockout, Reporter) |
Mutations: |
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Insertion, Intragenic deletion
Vector: L1L2_Bact_P
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Mutation details: The insertion of the L1L2_Bact_P cassette created a deletion of size 1102 starting at position 56024510 and ending at position 56025612 of Chromosome 14 (Genome Build GRCm39). This deletion results in the removal of functionally critical exon(s). The cassette is composed of an FRT site followed by lacZ sequence and a loxP site. This first loxP site is followed by a neomycin resistance gene under the control of the human beta-actin promoter, SV40 polyA, a second FRT site and a second loxP site.
(J:148605, J:173534)
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Original: |
J:148605 Wellcome Trust Sanger Institute, Alleles produced for the KOMP project by the Wellcome Trust Sanger Institute. MGI Direct Data Submission. 2009; |
All: |
5 reference(s) |
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