Nprl2tm1(KOMP)Wtsi
Targeted Allele Detail
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Symbol: |
Nprl2tm1(KOMP)Wtsi |
Name: |
NPR2 like, GATOR1 complex subunit; targeted mutation 1, Wellcome Trust Sanger Institute |
MGI ID: |
MGI:4419370 |
Gene: |
Nprl2 Location: Chr9:107419425-107422905 bp, + strand Genetic Position: Chr9, 58.12 cM, cytoband F1
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Alliance: |
Nprl2tm1(KOMP)Wtsi page
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IMPC: |
Nprl2 gene page |
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Mutant Cell Lines: |
EPD0401_2_D02, EPD0401_2_D03, EPD0401_2_F04, EPD0401_2_G03, EPD0401_2_H04 |
Germline Transmission: |
Earliest citation of germline transmission:
J:204812
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Parent Cell Line: |
JM8A3.N1 (ES Cell)
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Strain of Origin: |
C57BL/6N-Atm1Brd
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Project Collection: |
KOMP-CSD
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Allele Type: |
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Targeted (Null/knockout, Reporter) |
Mutations: |
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Insertion, Intragenic deletion
Vector: L1L2_Bact_P
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Mutation details: The insertion of the L1L2_Bact_P cassette created a deletion of size 2482 starting at position 107420129 and ending at position 107422611 of Chromosome 9 (Genome Build GRCm39). This deletion results in the removal of functionally critical exon(s). The cassette is composed of an FRT site followed by lacZ sequence and a loxP site. This first loxP site is followed by a neomycin resistance gene under the control of the human beta-actin promoter, SV40 polyA, a second FRT site and a second loxP site.
(J:148605, J:173534)
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Original: |
J:148605 Wellcome Trust Sanger Institute, Alleles produced for the KOMP project by the Wellcome Trust Sanger Institute. MGI Direct Data Submission. 2009; |
All: |
3 reference(s) |
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