Uchl3tm1(KOMP)Wtsi
Targeted Allele Detail
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Symbol: |
Uchl3tm1(KOMP)Wtsi |
Name: |
ubiquitin carboxyl-terminal esterase L3 (ubiquitin thiolesterase); targeted mutation 1, Wellcome Trust Sanger Institute |
MGI ID: |
MGI:4419341 |
Gene: |
Uchl3 Location: Chr14:101891403-101933561 bp, + strand Genetic Position: Chr14, 50.9 cM
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IMPC: |
Uchl3 gene page |
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Mutant Cell Lines: |
EPD0392_1_A05, EPD0392_1_A06, EPD0392_1_A07, EPD0392_1_B06, EPD0392_1_B08, EPD0392_1_C05, EPD0392_1_C06, EPD0392_1_C07, EPD0392_1_D05, EPD0392_1_D06, EPD0392_1_D07, EPD0392_1_E08, EPD0392_1_F05, EPD0392_1_F07, EPD0392_1_H05, EPD0392_1_H06 |
Germline Transmission: |
Unknown
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Parent Cell Line: |
JM8A3.N1 (ES Cell)
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Strain of Origin: |
C57BL/6N-Atm1Brd
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Project Collection: |
KOMP-CSD
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Allele Type: |
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Targeted (Null/knockout, Reporter) |
Mutations: |
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Insertion, Intragenic deletion
Vector: L1L2_Bact_P
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Mutation details: The insertion of the L1L2_Bact_P cassette created a deletion of size 2923 starting at position 101903156 and ending at position 101906079 of Chromosome 14 (Genome Build GRCm39). This deletion results in the removal of functionally critical exon(s). The cassette is composed of an FRT site followed by lacZ sequence and a loxP site. This first loxP site is followed by a neomycin resistance gene under the control of the human beta-actin promoter, SV40 polyA, a second FRT site and a second loxP site.
(J:148605, J:173534)
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Original: |
J:148605 Wellcome Trust Sanger Institute, Alleles produced for the KOMP project by the Wellcome Trust Sanger Institute. MGI Direct Data Submission. 2009; |
All: |
2 reference(s) |
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