Tg(Fabp4-Dgat1)2Far
Transgene Detail

Summary

• Symbol: Tg(Fabp4-Dgat1)2Far
• Name: transgene insertion 2, Robert V Farese
• MGI ID: MGI:4418728
• Synonyms: aP2-Dgat1
• Transgene: Tg(Fabp4-Dgat1)2Far Location: unknown
• Alliance: Tg(Fabp4-Dgat1)2Far page

Transgene origin

• Strain of Origin: C57BL/6J

Transgene description

• Transgene Type: Transgenic (Inserted expressed sequence)
• Mutation: Insertion
• Tg(Fabp4-Dgat1)2Far expresses 1 gene
  Transgene expresses:
  

  Organism	Expressed Gene	Note
  mouse	Dgat1 (MGI:1333825)

• Mutation details: A 5.4 kb promoter for Fabp4 was used to drive expression of a 1.6 kb murine Dgat1 cDNA which expresses an amino-terminal FLAG epitope. The transgene is expressed only in white adepose tissue. A high expressing line (line 2) and a low expressing line (line 3) were established. (J:107180)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available

References

• Original: J:107180 Chen HC, et al., Dissociation of obesity and impaired glucose disposal in mice overexpressing acyl coenzyme a:diacylglycerol acyltransferase 1 in white adipose tissue. Diabetes. 2002 Nov;51(11):3189-95
• All: 3 reference(s)