Tg(tetO-Tcra)1Doi
Transgene Detail

Summary

• Symbol: Tg(tetO-Tcra)1Doi
• Name: transgene insertion 1, Christophe Benoist and Diane Mathis
• MGI ID: MGI:4418669
• Synonyms: TAO
• Transgene: Tg(tetO-Tcra)1Doi Location: unknown
• Alliance: Tg(tetO-Tcra)1Doi page

Transgene origin

• Strain of Origin: (C57BL/6 x SJL)F2

Transgene description

• Transgene Type: Transgenic (Inducible, Inserted expressed sequence)
• Inducer: doxycycline/tetracycline
• Mutation: Insertion
• Mutation details: The transgene insert consists of the OT1 rearranged Tcra receptor (Valpha 2 and Jalpha 26) placed under the control of a tetO promoter composed of the CMV minimal promoter linked to 7 tetO sequences. The Tcra chain is part of a receptor specific for the ovalbumin peptide residues 257-264, H3K^b restricted. (J:70595)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 3 strains available Cell Lines: 0 lines available

References

• Original: J:70595 Labrecque N, et al., How much TCR does a T cell need?. Immunity. 2001 Jul;15(1):71-82
• All: 1 reference(s)