Tg(Camk2a-tTA)1Stl
Transgene Detail
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| Symbol: |
Tg(Camk2a-tTA)1Stl |
| Name: |
transgene insertion 1, Susumu Tonegawa |
| MGI ID: |
MGI:4418554 |
| Synonyms: |
alphaCamKII-loxP-STOP-loxP-tTA, Tg2 |
| Transgene: |
Tg(Camk2a-tTA)1Stl Location: unknown
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| Alliance: |
Tg(Camk2a-tTA)1Stl page
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| Transgene Type: |
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Transgenic (Transactivator) |
| Mutation: |
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Insertion
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Mutation details: The transgene construct contained the tetracycline transactivator (tTA) coding sequence downstream of a loxP-STOP-loxP fragement. This was inserted downstream of the alpha-CamKII (Camk2a) promoter in the final construct. Pronuclei of fertilized C57BL/6 eggs were injected with the purified linearized construct. A founder line 1 was established by backcrossing the founder with C57BL/6 mice.
(J:131852)
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| Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
| Carrying this Mutation: |
Mouse Strains: 1 strain available
Cell Lines: 0 lines available
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| Original: |
J:131852 Nakashiba T, et al., Transgenic inhibition of synaptic transmission reveals role of CA3 output in hippocampal learning. Science. 2008 Feb 29;319(5867):1260-4 |
| All: |
6 reference(s) |
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