Tg(KRT14-GAL4/PGR*/RELA*)1Xjw
Transgene Detail

Summary

• Symbol: Tg(KRT14-GAL4/PGR*/RELA*)1Xjw
• Name: transgene insertion 1, Xiao-Jing Wang
• MGI ID: MGI:4418071
• Synonyms: K14-GLp65
• Transgene: Tg(KRT14-GAL4/PGR*/RELA*)1Xjw Location: unknown
• Alliance: Tg(KRT14-GAL4/PGR*/RELA*)1Xjw page

Transgene origin

• Strain of Origin: ICR x (C57BL/6 x C3H)F1

Transgene description

• Transgene Type: Transgenic (Inserted expressed sequence)
• Mutation: Insertion
• Tg(KRT14-GAL4/PGR*/RELA*)1Xjw expresses 2 genes
  Transgene expresses:
  

  Organism

  Expressed Gene

  Homolog in Mouse

  Note

  human

  PGR (5241)

  Pgr	(MGI:97567)

  Transgene codes for a fusion protein of GAL4, PGR and RELA.

  human

  RELA (5970)

  Rela	(MGI:103290)

  Transgene codes for a fusion protein of GAL4, PGR and RELA.

• Mutation details: The human keratin 14 promoter was used to drive expression of the GLp65 fusion protein which is composed of yeast GAL4 DNA binding domain, the ligand binding domain of the truncated human progesteron receptor gene and the transactivation domain of human RELA (nuclear factor-kappaB p65). (J:75279)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available

References

• Original: J:75279 Cao T, et al., K14-GLp65 transactivator induces transgene expression in embryonic epidermis. Genesis. 2002 Feb;32(2):189-90
• All: 4 reference(s)