Tg(ACTB-TIMP1)1Werb
Transgene Detail

Summary

• Symbol: Tg(ACTB-TIMP1)1Werb
• Name: transgene insertion 1, Zena Werb
• MGI ID: MGI:4418045
• Transgene: Tg(ACTB-TIMP1)1Werb Location: unknown
• Alliance: Tg(ACTB-TIMP1)1Werb page

Transgene origin

• Strain of Origin: CD-1

Transgene description

• Transgene Type: Transgenic (Inserted expressed sequence)
• Mutation: Insertion
• Tg(ACTB-TIMP1)1Werb expresses 1 gene
  Transgene expresses:
  

  Organism

  Expressed Gene

  Homolog in Mouse

  Note

  human

  TIMP1 (7076)

  Timp1

  (MGI:98752)

• Mutation details: The human beta actin promoter was used to drive expression of a human cDNA construct located between the promoter and the beta actin 3' UTR. Human TIMP1 protein is present in the serum of transgenic mice at levels up to 50ng/ml. (J:155924)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available

References

• Original: J:155924 Alexander CM, et al., Rescue of mammary epithelial cell apoptosis and entactin degradation by a tissue inhibitor of metalloproteinases-1 transgene. J Cell Biol. 1996 Dec;135(6 Pt 1):1669-77
• All: 1 reference(s)