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Il15ratm2.1Ama
Targeted Allele Detail
Nomenclature
Symbol: Il15ratm2.1Ama
Name: interleukin 15 receptor, alpha chain; targeted mutation 2.1, Averil Ma
MGI ID: MGI:4417841
Synonyms: Il15rafl
Gene: Il15ra  Location: Chr2:11705172-11733985 bp, + strand  Genetic Position: Chr2, 8.97 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:155298
Parent Cell Line:  PRX-B6T (ES Cell)
Strain of Origin:  C57BL/6J
Mutation
description
Allele Type:    Targeted (Conditional ready, No functional change)
Mutation:    Insertion
 
Mutation detailsLoxP sites flanking exons 2 and 3 as well as an FRT flanked neomycin expression cassette were inserted by homologous recombination. The neomycin resistance cassette was then removed by flp mediated recombination. (J:155298)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Il15ra Mutation:  5 strains or lines available
References
Original:  J:155298 Mortier E, et al., Macrophage- and dendritic-cell-derived interleukin-15 receptor alpha supports homeostasis of distinct CD8+ T cell subsets. Immunity. 2009 Nov 20;31(5):811-22
All:  3 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
03/31/2020
MGI 6.15
The Jackson Laboratory