Pf4^{tm1(KOMP)Vlcg}
Targeted Allele Detail

Summary

• Symbol: Pf4^{tm1(KOMP)Vlcg}
• Name: platelet factor 4; targeted mutation 1, Velocigene
• MGI ID: MGI:4415543
• Gene: Pf4 Location: Chr5:90920362-90921242 bp, + strand Genetic Position: Chr5, 44.78 cM
• Alliance: Pf4^{tm1(KOMP)Vlcg} page
• IMPC: Pf4 gene page

Mutation origin

• Mutant Cell Lines: 12851A-A4, 12851A-B4, 12851A-C5, 12851A-C10, 12851A-D7
• Germline Transmission: Earliest citation of germline transmission: J:204812
• Parent Cell Line: VGB6 (ES Cell)
• Strain of Origin: C57BL/6NTac
• Project Collection: KOMP-Regeneron

Mutation description

• Allele Type: Targeted (Null/knockout, Reporter)
• Mutations: Insertion, Intragenic deletion Vector: ZEN-Ub1
• Mutation details: The insertion of Velocigene cassette ZEN-Ub1 created a deletion of size 736bp between positions 90920444-90921179 of Chromosome 5 (Build GRCm39). (J:136110)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 1 line available
• Carrying any Pf4 Mutation: 15 strains or lines available

References

• Original: J:136110 Velocigene, Alleles produced for the KOMP project by Velocigene (Regeneron Pharmaceuticals). MGI Direct Data Submission. 2008
• All: 2 reference(s)