Serpina12^{tm1(KOMP)Vlcg}
Targeted Allele Detail

Summary

• Symbol: Serpina12^{tm1(KOMP)Vlcg}
• Name: serine (or cysteine) peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 12; targeted mutation 1, Velocigene
• MGI ID: MGI:4415426
• Gene: Serpina12 Location: Chr12:103995028-104010702 bp, - strand Genetic Position: Chr12, 53.05 cM, cytoband F1
• Alliance: Serpina12^{tm1(KOMP)Vlcg} page
• IMPC: Serpina12 gene page

Mutation origin

• Mutant Cell Lines: 12138A-B3, 12138A-G2
• Germline Transmission: Earliest citation of germline transmission: J:204812
• Parent Cell Line: VGB6 (ES Cell)
• Strain of Origin: C57BL/6NTac
• Project Collection: KOMP-Regeneron

Mutation description

• Allele Type: Targeted (Null/knockout, Reporter)
• Mutations: Insertion, Intragenic deletion Vector: ZEN-Ub1
• Mutation details: The insertion of Velocigene cassette ZEN-Ub1 created a deletion of size 7525bp between positions 104001103-104008627 of Chromosome 12 (Build GRCm39). (J:136110)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 1 line available
• Carrying any Serpina12 Mutation: 33 strains or lines available

References

• Original: J:136110 Velocigene, Alleles produced for the KOMP project by Velocigene (Regeneron Pharmaceuticals). MGI Direct Data Submission. 2008
• All: 2 reference(s)