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Cd177tm1(KOMP)Vlcg
Targeted Allele Detail
Nomenclature
Symbol: Cd177tm1(KOMP)Vlcg
Name: CD177 antigen; targeted mutation 1, Velocigene
MGI ID: MGI:4415421
Gene: Cd177  Location: Chr7:24743983-24760311 bp, - strand  Genetic Position: Chr7, 12.58 cM
Mutation
origin
Mutant Cell Lines:  12120A-B11, 12120A-E8, 12120A-F2, 12120A-G10
Germline Transmission:  Earliest citation of germline transmission: J:204812
Parent Cell Line:  VGB6 (ES Cell)
Strain of Origin:  C57BL/6NTac
Project Collection: KOMP-Regeneron
Mutation
description
Allele Type:    Targeted (Null/knockout, Reporter)
Mutations:    Insertion, Intragenic deletion     Vector: ZEN-Ub1
 
Mutation detailsThe insertion of Velocigene cassette ZEN-Ub1 created a deletion of size 16087bp between positions 25529032-25545118 of Chromosome 7 (Genome Build37). The lacZ anf floxed neomycin resistance cassette replaced the coding sequence. FACS analysis confirmed the absence of protein on blood and bone marrow cells. (J:136110, J:225335)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Cd177 Mutation:  31 strains or lines available
References
Original:  J:136110 Velocigene, Alleles produced for the KOMP project by Velocigene (Regeneron Pharmaceuticals). MGI Direct Data Submission. 2008;
All:  3 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
03/24/2020
MGI 6.15
The Jackson Laboratory