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Targeted Allele Detail
Symbol: Rb1tm2.1Brn
Name: RB transcriptional corepressor 1; targeted mutation 2.1, Anton Berns
MGI ID: MGI:4415315
Synonyms: Rbdelta19
Gene: Rb1  Location: Chr14:73430298-73563446 bp, - strand  Genetic Position: Chr14, 38.73 cM, cytoband D3
Germline Transmission:  Earliest citation of germline transmission: J:77982
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  Not Specified
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
Mutation detailsThe floxed exon 19 was deleted from Rb1tm2Brn in the germ line by crossing with an actin-cre deleter strain. (J:77982)
View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Rb1 Mutation:  81 strains or lines available
Original:  J:77982 Vooijs M, et al., Tumor formation in mice with somatic inactivation of the retinoblastoma gene in interphotoreceptor retinol binding protein-expressing cells. Oncogene. 2002 Jul 11;21(30):4635-45
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
MGI 6.17
The Jackson Laboratory