Tg(Cd4-Il7r)1Wjl
Transgene Detail

Summary

• Symbol: Tg(Cd4-Il7r)1Wjl
• Name: transgene insertion 1, Warren J Leonard
• MGI ID: MGI:4415298
• Synonyms: Tg IL-7Ralpha
• Transgene: Tg(Cd4-Il7r)1Wjl Location: unknown
• Alliance: Tg(Cd4-Il7r)1Wjl page

Transgene origin

• Strain of Origin: C57BL/6

Transgene description

• Transgene Type: Transgenic (Inserted expressed sequence)
• Mutation: Insertion
• Tg(Cd4-Il7r)1Wjl expresses 1 gene
  Transgene expresses:
  

  Organism	Expressed Gene	Note
  mouse	Il7r (MGI:96562)

• Mutation details: Transgenic mice express a murine Il7r cDNA under the control of a CD4 enhancer/promoter, which lacks the CD4 silencer located in intron 1 and thus directs transgene expression in T lineage cells. (J:131561)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available

References

• Original: J:131561 Haring JS, et al., Constitutive Expression of IL-7 Receptor {alpha} Does Not Support Increased Expansion or Prevent Contraction of Antigen-Specific CD4 or CD8 T Cells following Listeria monocytogenes Infection. J Immunol. 2008 Mar 1;180(5):2855-62
• All: 2 reference(s)