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Targeted Allele Detail
Symbol: Ezh2tm1Yugo
Name: enhancer of zeste 2 polycomb repressive complex 2 subunit; targeted mutation 1, Yukiko Gotoh
MGI ID: MGI:4412411
Synonyms: Ezh2deltasetf, Ezh2SET-fl
Gene: Ezh2  Location: Chr6:47507208-47572309 bp, - strand  Genetic Position: Chr6, 22.92 cM, cytoband B
Germline Transmission:  Earliest citation of germline transmission: J:154927
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  Not Specified
Allele Type:    Targeted (Conditional ready, No functional change)
Mutation:    Insertion
Mutation detailsA floxed neo cassette was inserted upstream of exon 18 and an additional loxP site was inserted downstream of exon 19. (J:154927)
View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Ezh2 Mutation:  56 strains or lines available
Original:  J:154927 Hirabayashi Y, et al., Polycomb limits the neurogenic competence of neural precursor cells to promote astrogenic fate transition. Neuron. 2009 Sep 10;63(5):600-13
All:  23 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
MGI 6.21
The Jackson Laboratory