Prdx5^{tm1(KOMP)Vlcg}
Targeted Allele Detail

Summary

• Symbol: Prdx5^{tm1(KOMP)Vlcg}
• Name: peroxiredoxin 5; targeted mutation 1, Velocigene
• MGI ID: MGI:4399666
• Gene: Prdx5 Location: Chr19:6884065-6887474 bp, - strand Genetic Position: Chr19, 5.08 cM
• Alliance: Prdx5^{tm1(KOMP)Vlcg} page
• IMPC: Prdx5 gene page

Mutation origin

• Mutant Cell Lines: 13742A-C5, 13742A-G5, 13742A-G10, 13742A-H4
• Germline Transmission: Earliest citation of germline transmission: J:136110
• Parent Cell Line: VGB6 (ES Cell)
• Strain of Origin: C57BL/6NTac
• Project Collection: KOMP-Regeneron

Mutation description

• Allele Type: Targeted (Null/knockout, Reporter)
• Mutations: Insertion, Intragenic deletion Vector: ZEN-Ub1
• Mutation details: The insertion of Velocigene cassette ZEN-Ub1 created a deletion of size 2850bp between positions 6884133-6886982 of Chromosome 19 (Build GRCm39). The entire coding region of Prdx5 was replaced with a LacZ reporter gene and floxed neomycin resistance cassette. (J:136110)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 1 line available
• Carrying any Prdx5 Mutation: 18 strains or lines available

References

• Original: J:136110 Velocigene, Alleles produced for the KOMP project by Velocigene (Regeneron Pharmaceuticals). MGI Direct Data Submission. 2008
• All: 1 reference(s)