Mc1r^{tm1(KOMP)Vlcg}
Targeted Allele Detail

Summary

• Symbol: Mc1r^{tm1(KOMP)Vlcg}
• Name: melanocortin 1 receptor; targeted mutation 1, Velocigene
• MGI ID: MGI:4399474
• Gene: Mc1r Location: Chr8:124133846-124137483 bp, + strand Genetic Position: Chr8, 72.1 cM
• Alliance: Mc1r^{tm1(KOMP)Vlcg} page
• IMPC: Mc1r gene page

Mutation origin

• Mutant Cell Lines: 13037A-B6, 13037A-B10, 13037A-D1
• Germline Transmission: Earliest citation of germline transmission: J:204812
• Parent Cell Line: VGB6 (ES Cell)
• Strain of Origin: C57BL/6NTac
• Project Collection: KOMP-Regeneron

Mutation description

• Allele Type: Targeted (Null/knockout, Reporter)
• Mutations: Insertion, Intragenic deletion Vector: ZEN-Ub1
• Mutation details: The insertion of Velocigene cassette ZEN-Ub1 created a deletion of size 971bp between positions 124134252-124135222 of Chromosome 8 (Build GRCm39). (J:136110)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 1 line available
• Carrying any Mc1r Mutation: 43 strains or lines available

References

• Original: J:136110 Velocigene, Alleles produced for the KOMP project by Velocigene (Regeneron Pharmaceuticals). MGI Direct Data Submission. 2008
• All: 2 reference(s)