Gpbar1^{tm1(KOMP)Vlcg}
Targeted Allele Detail

Summary

• Symbol: Gpbar1^{tm1(KOMP)Vlcg}
• Name: G protein-coupled bile acid receptor 1; targeted mutation 1, Velocigene
• MGI ID: MGI:4399435
• Gene: Gpbar1 Location: Chr1:74317709-74318783 bp, + strand Genetic Position: Chr1, 38.53 cM
• Alliance: Gpbar1^{tm1(KOMP)Vlcg} page
• IMPC: Gpbar1 gene page

Mutation origin

• Mutant Cell Lines: 12939A-C6, 12939A-D8, 12939A-F12, 12939A-H7
• Germline Transmission: Earliest citation of germline transmission: J:204812
• Parent Cell Line: VGB6 (ES Cell)
• Strain of Origin: C57BL/6NTac
• Project Collection: KOMP-Regeneron

Mutation description

• Allele Type: Targeted (Null/knockout, Reporter)
• Mutations: Insertion, Intragenic deletion Vector: ZEN-Ub1
• Mutation details: The insertion of Velocigene cassette ZEN-Ub1 created a deletion of size 1090bp between positions 74317762-74318851 of Chromosome 1 (Build GRCm39). (J:136110)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 2 strains available Cell Lines: 1 line available
• Carrying any Gpbar1 Mutation: 28 strains or lines available

References

• Original: J:136110 Velocigene, Alleles produced for the KOMP project by Velocigene (Regeneron Pharmaceuticals). MGI Direct Data Submission. 2008
• All: 9 reference(s)