Tmem35a^{tm1(KOMP)Vlcg}
Targeted Allele Detail

Summary

• Symbol: Tmem35a^{tm1(KOMP)Vlcg}
• Name: transmembrane protein 35A; targeted mutation 1, Velocigene
• MGI ID: MGI:4399235
• Gene: Tmem35a Location: ChrX:133195974-133206718 bp, + strand Genetic Position: ChrX, 56.06 cM
• Alliance: Tmem35a^{tm1(KOMP)Vlcg} page
• IMPC: Tmem35a gene page

Mutation origin

• Mutant Cell Lines: 11586A-A5, 11586B-B9, 11586B-D4
• Germline Transmission: Earliest citation of germline transmission: J:244268
• Parent Cell Line: VGB6 (ES Cell)
• Strain of Origin: C57BL/6NTac
• Project Collection: KOMP-Regeneron

Mutation description

• Allele Type: Targeted (Null/knockout, Reporter)
• Mutations: Insertion, Intragenic deletion Vector: ZEN-Ub1
• Mutation details: The insertion of Velocigene cassette ZEN-Ub1 (containing the lacZ reporter gene and a loxP site flanked neomycin resistance gene cassette) created a deletion of size 9360bp between positions 133196244-133205603 of Chromosome X (Build GRCm39). This deletes most of the two-exon coding region. (J:136110)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 2 strains available Cell Lines: 1 line available
• Carrying any Tmem35a Mutation: 5 strains or lines available

References

• Original: J:136110 Velocigene, Alleles produced for the KOMP project by Velocigene (Regeneron Pharmaceuticals). MGI Direct Data Submission. 2008
• All: 6 reference(s)