Acvr1b^{tm1(KOMP)Vlcg}
Targeted Allele Detail

Summary

• Symbol: Acvr1b^{tm1(KOMP)Vlcg}
• Name: activin A receptor, type 1B; targeted mutation 1, Velocigene
• MGI ID: MGI:4399226
• Gene: Acvr1b Location: Chr15:101071953-101111565 bp, + strand Genetic Position: Chr15, 56.48 cM
• Alliance: Acvr1b^{tm1(KOMP)Vlcg} page
• IMPC: Acvr1b gene page

Mutation origin

• Mutant Cell Lines: 11377A-A5, 11377A-A6, 11377A-G12, 11377A-H6
• Germline Transmission: Earliest citation of germline transmission: J:204812
• Parent Cell Line: VGB6 (ES Cell)
• Strain of Origin: C57BL/6NTac
• Project Collection: KOMP-Regeneron

Mutation description

• Allele Type: Targeted (Null/knockout, Reporter)
• Mutations: Insertion, Intragenic deletion Vector: TM-ZEN-Ub1
• Mutation details: The insertion of Velocigene cassette TM-ZEN-Ub1 created a deletion of size 16930bp between positions 101091815-101108744 of Chromosome 15 (Build GRCm39). (J:136110)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 1 line available
• Carrying any Acvr1b Mutation: 36 strains or lines available

References

• Original: J:136110 Velocigene, Alleles produced for the KOMP project by Velocigene (Regeneron Pharmaceuticals). MGI Direct Data Submission. 2008
• All: 2 reference(s)