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Tg(CAG-dre)1Afst
Transgene Detail
Nomenclature
Symbol: Tg(CAG-dre)1Afst
Name: transgene insertion 1, A Francis Stewart
MGI ID: MGI:4367446
Synonyms: CAG-Dre, CAGGs-Dre
Transgene: Tg(CAG-dre)1Afst  Location: unknown  
Transgene
origin
Germline Transmission:  Earliest citation of germline transmission: J:154134
Parent Cell Line:  R1 (ES Cell)
Strain of Origin:  (129X1/SvJ x 129S1/Sv)F1-Kitl+
Transgene
description
Transgene Type:    Transgenic (Recombinase)
Mutation:    Insertion
 
Mutation detailsA plasmid in which the CAG (CAGGS) promoter drives the bacteriophage D6 site-specific recombinase (dre). This is followed by an IRES-puromycin sequence for selection. The linearized construct was electroporated into R1 ES cells, and single-copy clones were injected into 8-cell embryos. Germline transmission was obtained for one of these clones. (J:154134)
Recombinase
activity
Activity:
 Tissue activity of this recombinase allele
Driver: CAG     Summary of all recombinase alleles driven by CAG.
 

Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 2 strains available      Cell Lines: 0 lines available
References
Original:  J:154134 Anastassiadis K, et al., Dre recombinase, like Cre, is a highly efficient site-specific recombinase in E. coli, mammalian cells and mice. Dis Model Mech. 2009 Sep-Oct;2(9-10):508-15
All:  17 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
01/18/2022
MGI 6.17
The Jackson Laboratory