Gt(ROSA)26Sor^{tm1.1(CAG-ECFP/Venus)Kgwa}
Targeted Allele Detail

Summary

• Symbol: Gt(ROSA)26Sor^{tm1.1(CAG-ECFP/Venus)Kgwa}
• Name: gene trap ROSA 26, Philippe Soriano; targeted mutation 1.1, Osami Kanagawa
• MGI ID: MGI:4366504
• Synonyms: Gt(ROSA)26Sor^{tm1.1(CAG-ECFP/EYFP*)Kgwa}, ROSA-CAG-SCAT3.1
• Gene: Gt(ROSA)26Sor Location: Chr6:113044389-113054205 bp, - strand Genetic Position: Chr6, 52.73 cM
• Alliance: Gt(ROSA)26Sor^{tm1.1(CAG-ECFP/Venus)Kgwa} page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:153768
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: (C57BL/6 x DBA/2)F1

Mutation description

• Allele Type: Targeted (Reporter)
• Mutation: Insertion
• Mutation details: Germ line, cre recombination removes the upstream floxed STOP cassette inserted into the locus allowing CAG-driven expression of SCAT3.1 (an apoptosis-sensitive reporter composed of a fusion of ECFP and the Venus EYFP analog connected by a caspase 3 cleavable peptide). (J:153768)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Gt(ROSA)26Sor Mutation: 945 strains or lines available

References

• Original: J:153768 Tomura M, et al., Time-lapse observation of cellular function with fluorescent probe reveals novel CTL-target cell interactions. Int Immunol. 2009 Oct;21(10):1145-50
• All: 3 reference(s)