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Hmgn3tm1.2Mbus
Targeted Allele Detail
Nomenclature
Symbol: Hmgn3tm1.2Mbus
Name: high mobility group nucleosomal binding domain 3; targeted mutation 1.2, Michael Bustin
MGI ID: MGI:4366465
Synonyms: Hmgn3tm1
Gene: Hmgn3  Location: Chr9:83109948-83146685 bp, - strand  Genetic Position: Chr9, 45.29 cM, cytoband E3.1
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:153774
Parent Cell Line:  v6.4 (ES Cell)
Strain of Origin:  (C57BL/6J x 129S4/SvJae)F1
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsGerm line, cre mediated recombination removed exons 3 and 4. The absence of protein expression was confirmed by western blot analysis on brain, medulla oblongata, liver, and testis extracts. (J:153774)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Structures Affected by this Mutation: 1 anatomical structures
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Hmgn3 Mutation:  5 strains or lines available
References
Original:  J:153774 Ueda T, et al., The nucleosome binding protein HMGN3 modulates the transcription profile of pancreatic beta cells and affects insulin secretion. Mol Cell Biol. 2009 Oct;29(19):5264-76
All:  4 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
11/05/2019
MGI 6.14
The Jackson Laboratory